Bilateral non granulomatous anterior uveitis and optic disc oedema in a patient with retinitis pigmentosa
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Yes
Purpose
To report a case of bilateral non granulomatous anterior uveitis and optic disc oedema in a patient with retinitis pigmentosa (RP).
Methods
An 18-year-old male presented to the emergency department complaining of left eye photophobia, redness and pain for few hours. Past medical history included spasmus nutans. Visual acuity was 5/10 in the right eye and 4/10 in the left eye. Relative afferent pupillary defect was negative and color vision was full in both eyes. Anterior segment examination showed cells +1 in the right eye and +2 in the left eye with normal intraocular pressure. Dilated examination showed typical signs of RP, mild vitritis and indistinct optic disc margins in both eyes. Macula appeared unaffected.
Results
Autofluorescence and visual fields examinations were typical for RP and fluorescein angiogram showed disc leakage with no signs of peripheral vasculitis in either eye. Ocular ultrasound was unremarkable. Brain MRI and chest X-ray were normal as well and screening for infectious and autoimmune diseases was negative. Blood pressure and body mass index were normal. Neurological and rheumatological consultations did not reveal any pathology although patient refused to undergo lumbar puncture. Due to the optic disc oedema we decided to administer one gram per day of methylprednisolone intravenously for three days and then switch to oral steroids. He was also given topical dexamethasone 0,1% and cyclopentolate 1% drops in both eyes.
On follow-up, visual acuity improved significantly in both eyes as well as the signs of inflammation.
Conclusion
Uveitis in RP patients is not uncommon. This is another case to support the possible inflammatory pathway in the etiology of RP.
Conflict of interest
No
1
Last name
LIOLIOS
Initials of first name(s)
V
Department
Ophthalmology Dept , Konstantopouleio General Hospital
City
Athens
Country
Greece
2
Last name
Chatzirallis
Initials of first name(s)
A
Department
Ophthalmology Dept , Konstantopouleio General Hospital
City
Athens
Country
Greece
3
Last name
Giakoumogiannaki
Initials of first name(s)
E
Department
Ophthalmology Dept , Konstantopouleio General Hospital
City
Athens
Country
Greece
4
Last name
Andreopoulou
Initials of first name(s)
I
Department
Ophthalmology Dept , Konstantopouleio General Hospital
City
Athens
Country
Greece
5
Last name
Dalianis
Initials of first name(s)
G
Department
Ophthalmology Dept , Konstantopouleio General Hospital
City
Athens
Country
Greece
6
Last name
Terzidou
Initials of first name(s)
C
Department
Ophthalmology Dept , Konstantopouleio General Hospital
City
Athens
Country
Greece
7
Last name
Leivadeas
Initials of first name(s)
P
Department
Neurology Dept, Konstantopouleio General Hospital
City
Athens
Country
Greece
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