En face slab optical coherence tomography for uveitic eyes with normal appearance on color fundus photography
Purpose
To evaluate the damage to the innermost retina in uveitic eyes by en face slab optical coherence tomography (OCT).
Methods
We retrospectively reviewed 36 eyes with quiescent uveitis that do not show obvious macular abnormalities on color fundus photography (CFP) and have image datasets acquired by Cirrus HD-OCT and PLEX Elite 9000. Using the OCT image datasets, 2-dimensional en face slab OCT images of the innermost retina were reconstructed and graded from 0 (no damage) to 3 (severe damage) according to the ratio of dark area to total area, and the distribution of grades was calculated.
Results
The causes of uveitis were sarcoidosis (14%), Behçet's disease (14%), Vogt-Koyanagi-Harada disease (11%), others (17%), and unclassified (44%). The distribution of en face slab OCT grades was grade 0 (39%), grade 1 (36%), grade 2 (14%), and grade 3 (11%) on Cirrus HD-OCT and grade 0 (31%), grade 1 (39%), grade 2 (14%), and grade 3 (17%) on PLEX Elite 9000. Agreement of OCT grade between the two OCT models was 72%.
Conclusion
En face slab OCT is a useful modality to evaluate the damage to the innermost retina in uveitic eyes because it could detect abnormal OCT signals in 80-90% of the eyes with no apparent macular abnormality on conventional CFP.
Conflict of interest
No
Authors 1
Last name
KUSUHARA
Initials of first name(s)
S
Department
Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine
City
Kobe
Country
Japan
Authors 2
Last name
Matsumiya
Initials of first name(s)
W
Department
Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine
City
Kobe
Country
Japan
Authors 3
Last name
Nakamura
Initials of first name(s)
M
Department
Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine
City
Kobe
Country
Japan
This website uses cookies to ensure you get the best experience on our website.
Learn more