To report the clinical features of viral uveitis (VU)
Methods
Patients with VU referred to our department from February 2019 to January 2021 were included in a prospective observational study. Ophthalmic examination and appropriate laboratory investigations were completed. Polymerase chain reaction analysis of aqueous humor samples (PCR-AH) was performed when needed.
Results
Nineteen patients were included. The mean age was 47 years, 9 were female and 10 were male. Herpes viridae represented 90% of VU (n=17): Herpes simplex (HSV n=10), Varicella zoster viruses (VZV n=5) and Cytomegalovirus (CMV n=2). Other less frequent causes were Measles (MV n=1) and Human immunodeficiency viruses (HIV n=1). Ocular involvement was unilateral in all cases. HSV uveitis was anterior in all cases and granulomatous in 4 eyes. Corneal hypoesthesia (n=4), posterior synechiae (n=7), sectoral iris atrophy (n=4), ocular hypertension (n=4) and dendritic ulcer (n=7), were noted. The diagnosis was clinical in 6 eyes, and based on PCR-AC in 4 eyes. In the VZV group, isolated granulomatous panuveitis was noted in 3 cases and the diagnosis was based on PCR-AH.
Conclusion
There is a wide range of clinical features of VU with overlapping manifestations in different viruses. PCR-AH can be a valuable tool to identify the pathogen
Conflict of interest
No
Authors 1
Last name
MAAMOURI
Initials of first name(s)
RYM
Department
OPHTHALMOLOGY
City
Tunis
Country
Tunisia
Authors 2
Last name
BELDI
Initials of first name(s)
M
Department
Family medicine department
City
Tunis
Country
Tunisia
Authors 3
Last name
HOUMAN
Initials of first name(s)
Y
Department
OPHTHALMOLOGY
City
Tunis
Country
Tunisia
Authors 4
Last name
MHALLA
Initials of first name(s)
S
Department
Department of microbiology
City
MONASTIR
Country
Tunisia
Authors 5
Last name
OUEDERNI
Initials of first name(s)
M
Department
OPHTHALMOLOGY
City
Tunis
Country
Tunisia
Authors 6
Last name
CHEOUR
Initials of first name(s)
M
Department
OPHTHALMOLOGY
City
Tunis
Country
Tunisia
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