The aim of this presentation is to draw the attention to a heterogeneous group of rare autoimmune inflammatory diseases, where the clinical finding is dominated by an eruption, often typical for a given syndrome of the present multifocal microgranuloma in the choroidea, retinal pigment epithelium and the neuroretina.
Methods
The syndromes are not attached to a systemic autoimmune disease. Most often they are an isolated bilateral eye disorder. This disorder can be divided in two groups with different prognosis. Monitoring of the disease activity is aided not only by the fundus photography in time, but also by autofluorescence, fluorescein and indocyanine angiography and OCT examinations. During differential diagnosis it is important to think about the granulomatous chorioretintis in the context of sarcoidosis, TBC, sympathetic ophthalmia, toxoplasmosis or the masking syndrome.
Results
During treatment we administer corticosteroids perorally or by injection, we use immunosuppressants or biological therapy, or anti-VEGF treatment by injection into the eye in case a choroidal neovascularization develops.
Conclusion
Even though WDS disease is rare, we should take it into account while working with the differential diagnosis of bilateral multifocal chorioretintis. In case of progressive syndromes early treatment can stabilize the disease.
Conflict of interest
No
Author 1
Last name
KARKANOVA
Initials of first name(s)
M
Department
Faculty Hospital Ophthalmology and Medical Faculty at Masaryk University, Brno
City
Brno
Country
Czech Republic
Author 2
Last name
Beránek
Initials of first name(s)
J
Department
Faculty Hospital Ophthalmology and Medical Faculty at Masaryk University, Brno
City
Brno
Country
Czech Republic
Author 3
Last name
Vysloužilová
Initials of first name(s)
D
Department
Faculty Hospital Ophthalmology and Medical Faculty at Masaryk University, Brno
City
Brno
Country
Czech Republic
Author 4
Last name
Vlková
Initials of first name(s)
E
Department
Faculty Hospital Ophthalmology and Medical Faculty at Masaryk University, Brno
City
Brno
Country
Czech Republic
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