This abstract is assigned to sessions
| Presentation preference | Poster and Rapid fire |
| Title | Inflammation and Retinoblastoma |
| Accept poster if oral is not possible ? | Yes |
| Purpose | To study a case series of pathological evidence of inflammation in retinoblastoma eyes |
| Methods | Design-A laboratory based retrospective study.
Six enucleated eyeballs of retinoblastoma (Group E RB) was studied in details out of 61 RB cases from 2002-2018. Main and lateral calottes were examined for the inflammation other than necrosis. Pre - enucleation treatment in the cases were compared with the findings.
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| Results | There were (n=5) cases of undifferentiated RB showed chronic inflammation, one (n=1) case of differentiated RB with classical rosettes and mixed reaction; (n=4) was endophytic; (n=1) was exophytic and (n=1) was diffuse RB. All patients received 6 cycles chemotherapy. |
| Conclusion | Inflammation in RB can be induced by local or systemic treatment of RB. Tumor biology itself may undergo innate immune mechanism to induce such reaction. Characteristics of most of them were chronic inflammatory cells infiltrate. |
| Conflict of interest | No |
Author 1
| Last name | DAS |
| Initials of first name(s) | D |
| Department | Uveitis, Ocular Pathology & Neuro-Ophthalmology Services, Sri Sankaradeva Nethralaya |
| City | GUWAHATI |
| Country | India |
Author 2
| Last name | Deka |
| Initials of first name(s) | P |
| Department | Ocular Pathology, Sri Sankaradeva Nethralaya |
| City | GUWAHATI |
| Country | India |
Author 3
| Last name | Bhattacharjee |
| Initials of first name(s) | K |
| Department | Orbit and Oculoplasty, Sri Sankaradeva Nethralaya |
| City | GUWAHATI |
| Country | India |
Author 4
| Last name | Barman |
| Initials of first name(s) | MJ |
| Department | Vitreoretina, Sri Sankaradeva Nethralaya |
| City | Guwahati |
| Country | India |
Author 5
| Last name | Das |
| Initials of first name(s) | JK |
| Department | Orbit & Oculoplasty, Sri Sankaradeva Nethralaya |
| City | GUWAHATI |
| Country | India |
Author 6
| Last name | Kuri |
| Initials of first name(s) | GK |
| Department | Orbit & Oculoplasty, Sri Sankaradeva Nethralaya |
| City | GUWAHATI |
| Country | India |
Author 7
| Last name | Bhattacharjee |
| Initials of first name(s) | H |
| Department | Vitroretina, Sri Sankaradeva Nethralaya |
| City | GUWAHATI |
| Country | India |
Author 8
| Last name | Deka |
| Initials of first name(s) | A |
| Department | Ocular Pathology, Sri Sankaradeva Nethralaya |
| City | GUWAHATI |
| Country | India |
