To study a case series of pathological evidence of inflammation in retinoblastoma eyes
Methods
Design-A laboratory based retrospective study.
Six enucleated eyeballs of retinoblastoma (Group E RB) was studied in details out of 61 RB cases from 2002-2018. Main and lateral calottes were examined for the inflammation other than necrosis. Pre - enucleation treatment in the cases were compared with the findings.
Results
There were (n=5) cases of undifferentiated RB showed chronic inflammation, one (n=1) case of differentiated RB with classical rosettes and mixed reaction; (n=4) was endophytic; (n=1) was exophytic and (n=1) was diffuse RB. All patients received 6 cycles chemotherapy.
Conclusion
Inflammation in RB can be induced by local or systemic treatment of RB. Tumor biology itself may undergo innate immune mechanism to induce such reaction. Characteristics of most of them were chronic inflammatory cells infiltrate.
Conflict of interest
No
Author 1
Last name
DAS
Initials of first name(s)
D
Department
Uveitis, Ocular Pathology & Neuro-Ophthalmology Services, Sri Sankaradeva Nethralaya
City
GUWAHATI
Country
India
Author 2
Last name
Deka
Initials of first name(s)
P
Department
Ocular Pathology, Sri Sankaradeva Nethralaya
City
GUWAHATI
Country
India
Author 3
Last name
Bhattacharjee
Initials of first name(s)
K
Department
Orbit and Oculoplasty, Sri Sankaradeva Nethralaya
City
GUWAHATI
Country
India
Author 4
Last name
Barman
Initials of first name(s)
MJ
Department
Vitreoretina, Sri Sankaradeva Nethralaya
City
Guwahati
Country
India
Author 5
Last name
Das
Initials of first name(s)
JK
Department
Orbit & Oculoplasty, Sri Sankaradeva Nethralaya
City
GUWAHATI
Country
India
Author 6
Last name
Kuri
Initials of first name(s)
GK
Department
Orbit & Oculoplasty, Sri Sankaradeva Nethralaya
City
GUWAHATI
Country
India
Author 7
Last name
Bhattacharjee
Initials of first name(s)
H
Department
Vitroretina, Sri Sankaradeva Nethralaya
City
GUWAHATI
Country
India
Author 8
Last name
Deka
Initials of first name(s)
A
Department
Ocular Pathology, Sri Sankaradeva Nethralaya
City
GUWAHATI
Country
India
This website uses cookies to ensure you get the best experience on our website.
Learn more