Injectable 0.19-mg FAc implant for the treatment of non-infectious uveitic macular edema
Accept poster if oral is not possible ?
Yes
Purpose
A retrospective observational clinical study to evaluate the safety and effectiveness of the injectable 0.19-mg fluocinolone acetonide intravitreal implant (ILUVIEN; FAc) in the treatment of non-infectious uveitic macular edema.
Methods
Data are presented from eight patients (11 eyes) with non-infectious uveitic macular edema who were treated with FAc. Effectiveness and safety were assessed from changes in central retinal thickness (CRT), corrected distance visual acuity (BCVA), uveitic activity, and intraocular pressure.
Results
In 11/11 eyes, CRT improved between months 1 and 3. The mean maximum decrease of CRT throughout the follow-up period was 168 ± 202 μm (± standard deviation). Nine out of 11 eyes showed an improvement in BCVA (between + 1 and + 8 lines), and 2/11 eyes lost BCVA (- 1 and - 3 lines, respectively). Ten out of 11 eyes presented with inactive inflammation during the follow-up period.
Conclusion
In this small case series with long-term follow-up, treatment of non-infectious uveitic macular edema with the FAc was associated with improved CRT and BCVA and a manageable safety profile. The advantage of this device is the long-term drug release and the fact that it can be injected into the vitreous as a minor surgical procedure, which is in contrast to other treatment options.
Conflict of interest
Yes
Details of conflicting interests
Allergan: Travel fees and lecture fees
Alimera: Research, travel fees and lecture fees
Author 1
Last name
KHORAMNIA
Initials of first name(s)
R
Department
University Eye Clinic Heidelberg
City
Heidelberg
Country
Germany
Author 2
Last name
Weber
Initials of first name(s)
L
Department
University Eye Clinic Heidelberg
City
Heidelberg
Country
Germany
Author 3
Last name
Scheuerle
Initials of first name(s)
A
Department
University Eye Clinic Heidelberg
City
Heidelberg
Country
Germany
Author 4
Last name
Tandogan
Initials of first name(s)
T
Department
University Eye Clinic Heidelberg
City
Heidelberg
Country
Germany
Author 5
Last name
Mayer
Initials of first name(s)
C
Department
University Eye Clinic Heidelberg
City
Heidelberg
Country
Germany
Author 6
Last name
Marx
Initials of first name(s)
S
Department
University Eye Clinic Heidelberg
City
Heidelberg
Country
Germany
Author 7
Last name
Auffarth
Initials of first name(s)
G
Department
University Eye Clinic Heidelberg
City
Heidelberg
Country
Germany
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