This abstract is assigned to sessions
| Title | Rapid course of CNV and response to treatment in a case of PIC |
| Accept poster if oral is not possible ? | Yes |
| Purpose | To report the rapid course of choroidal neovascularization(CNV) and its response to intravitreal injection(IVI) of aflibercept in a case of punctate inner choroidopathy(PIC). |
| Methods | Case report |
| Results | A 22-year-old woman presented with blurred vision and central scotoma in the right eye(RE) for 1 year and left eye(LE) in recent 2 weeks. Best corrected visual acuity was 0.3(RE, -6.25 -1.00 X 170) and 0.5(LE, -6.25 -1.50 X 180). Ocular examination showed bilateral yellowish white chorioretinal lesions at posterior pole without ocular inflammation. There was more pigmentation in RE than LE. SD-OCT showed retinal pigment epithelium(RPE) disruption and hyperreflective material in both eyes as well as RPE detachment in RE. OCT angiography(OCTA) detected a large CNV at right macula, while a suspicious tiny one at left macula. Fundus fluorescein angiography(FAG) showed staining of the above lesions and leaking CNV at late phase RE>LE. 1 week after FAG, her vision dropped with obvious CNV in LE. IVI aflibercept(2mg/0.05 ml) of LE combining oral steroid was given. 3 days later, the CNV size decreased a lot on OCTA with vision improved to 0.8. IVI aflibercept of RE was given with slow tapering of oral steroid and she kept follow-up by slit lamp exam and OCTA in our clinic. |
| Conclusion | Like other uveitis related CNV, the CNV in PIC is sometimes difficult to be detected and measured in FAG. OCTA has advantages of three-dimensional view of retinal and choroidal vessels without interference by dye leakage or staining in FAG. We reported a case of PIC, which had distinct features of CNV progression and response to treatment demonstrated by OCTA. |
| Conflict of interest | No |
Author 1
| Last name | WANG |
| Initials of first name(s) | TW |
| Department | Department of Ophthalmology, KSVGH |
| City | Kaohsiung |
| Country | Taiwan |
Author 2
| Last name | Sheu |
| Initials of first name(s) | SJ |
| Department | Department of Ophthalmology, KSVGH |
| City | Kaohsiung |
| Country | Taiwan |
