Multimodal treatment of Idiopathic Retinal Vasculitis, Aneurisms, and Neuroretinitis (IRVAN)
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Yes
Purpose
Idiopathic Retinal Vasculitis, Aneurisms, and Neuroretinitis (IRVAN syndrome) is a rare retinal disorder that requires multimodal approach in treatment of this challenging clinical entity.
Methods
We report two cases (four eyes) of IRVAN syndrome.
Here we present two clinical cases (four eyes) of young patients with IRVAN syndrome who were treated in our clinic during current year. The first patient was 39 years old man with IRVAN syndrome stage 2 for right eye (RE) and stage 3 for left eye (LE). The second patient was 26 years old woman with stage 3 for RE and stage 4 for LE. Treatment approach was based on IRVAN syndrome staging.
Results
All eyes were treated with extensive pan retinal laser photocoagulation. Three eyes received intravitreal bevacizumab injection for peripheral retinal and optic disc neovascularisation. Two eyes received intravitreal dexamethason implant for macular oedema. One eye required vitrectomy due to perisistant intravitreal hemorrhage. The visual outcomes varied. The male patient maintained good visual outcomes (Snellen: right eye 6/6; left eye 6/9,5). The female patient had poorer visual outcomes due to ischemic maculopathy (Snellen: right eye 6/12; left eye 6/24) while pertaining stabile peripheral retinal findings.
Conclusion
Treatment of IRVAN syndrome is challenging. It requires individualized approach and multimodal treatment based on retinal findings and disease staging in order to maintain good visual outcomes.
Conflict of interest
No
1
Last name
MAVIJA
Initials of first name(s)
M
Department
University Ophthalmology Clinic, University Clinical Center of the Republic of Srpska
City
Banja Luka
Country
Bosnia and Herzegovina
2
Last name
MARKIC
Initials of first name(s)
B
Department
University Ophthalmology Clinic, University Clinical Center of the Republic of Srpska
City
Banja Luka
Country
Bosnia and Herzegovina
3
Last name
TOPIC
Initials of first name(s)
B
Department
University Ophthalmology Clinic, University Clinical Center of the Republic of Srpska
City
Banja Luka
Country
Bosnia and Herzegovina
4
Last name
TEPIC POPOVIC
Initials of first name(s)
M
Department
University Ophthalmology Clinic, University Clinical Center of the Republic of Srpska
City
Banja Luka
Country
Bosnia and Herzegovina
5
Last name
BURGIC
Initials of first name(s)
S
Department
University Ophthalmology Clinic, University Clinical Center of the Republic of Srpska
City
Banja Luka
Country
Bosnia and Herzegovina
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