Rifabutin-Induced panuveitis in a HIV-Positive Patient
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Yes
Purpose
To report a case of acute bilateral panuveitis in a HIV-positive patient with pulmonary tuberculosis, highlighting the importance of considering drug-induced uveitis in the differential diagnosis.
Methods
A case report of a 30-year-old male with AIDS and pulmonary tuberculosis who developed acute bilateral panuveitis. The patient's medical history, clinical presentation, laboratory investigations, and treatment course were reviewed.
Results
The patient presented with decreased visual acuity and ocular inflammation. Despite extensive workup, including aqueous analysis, no intraocular infectious etiology was identified. Following discontinuation of rifabutin and initiation of corticosteroids, the patient's symptoms resolved, and no recurrence was observed during the follow-up period.
Conclusion
Drug-induced uveitis should be considered in HIV-positive patients with panuveitis, especially when other common infectious causes have been excluded. Prompt recognition and appropriate management can prevent vision loss and improve patient outcomes.
Conflict of interest
No
1
Last name
LAI
Initials of first name(s)
YJ
Department
Department of Ophthalmology, MacKay memorial hospital
City
Taipei
Country
Taiwan
2
Last name
Chang
Initials of first name(s)
CF
Department
Department of Ophthalmology, MacKay memorial hospital
City
Taipei
Country
Taiwan
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