Characterization of Fluorescein Angiography Features in Pediatric Patients with Uveitis
Purpose
To characterize fluorescein angiography (FA) features in pediatric uveitis.
Methods
A retrospective cross-sectional study of pediatric uveitis patients in Atlanta, GA, who had FA imaging between May 2009 and August 2020.
Results
A total of 137 eyes of 88 patients were evaluated. The mean FA score in anterior uveitis was lower than that in other categories (p=0.0093). The mean FA score in the clinically active group was higher than that in the clinically inactive group (p=0.0057). The mean FA score in eyes 20/40 or better was lower than that in other categories (p=0.0292). Worse visual acuity was associated with retinal vascular staining/leakage, retinal staining/pooling, and neovascularization elsewhere. Non-infectious uveitis more often demonstrated optic disc hyperfluorescence, retinal vascular staining/leakage, capillary leakage, and pinpoint leaks, while infectious uveitis more often demonstrated retinal staining/pooling.
Conclusion
A standardized quantitative FA scoring system can be useful in the characterization of uveitis in pediatric patients.
Conflict of interest
No
Authors 1
Last name
HOSSAIN
Initials of first name(s)
HA
Department
Emory University School of Medicine Department of Ophthalmology
City
Atlanta
Country
United States
Authors 2
Last name
Ye
Initials of first name(s)
S
Department
Medical College of Georgia at Augusta University
City
Augusta
Country
United States
Authors 3
Last name
Ward
Initials of first name(s)
L
Department
Emory University Rollins School of Public Health
City
Atlanta
Country
United States
Authors 4
Last name
O'Keefe
Initials of first name(s)
G
Department
Emory University School of Medicine Department of Ophthalmology
City
Atlanta
Country
United States
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