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Presentation preference	Poster presentation
Title	Multiple evanescent white dot syndrome following BNT162b2 mRNA COVID-19 vaccination.

Purpose	To report a case with multiple evanescent white dot syndrome (MEWDS) following COVID-19 vaccination.
Methods	Case presentation
Results	Case : A 67-year-old female presented with central visual field loss in the right eye (OD) for 5 days since one day after second dose of BNT162b2 mRNA COVID-19 vaccine. At the initial visit, best corrected visual acuity (BCVA) in decimal points was 0.2 OD and 1.0 in the left eye (OS). Ophthalmic examination showed multifocal white dots in the posterior retina OD. Multimodal imaging OD showed diffuse disruption of ellipsoid zone on OCT, punctate hyperfluorescence in a wreath-like pattern and late staining on fluorescein angiography, and multiple hypofluorescent spots in the late phases on indocyanine green angiography. One week later, there were disappearing multifocal white dots OD. No active intraocular inflammation or abnormality had been seen in the left eye. One more week later, her BCVA OD was spontaneously improved to 0.8 without any treatment. Collectively, these clinical findings led to the diagnosis of MEWDS after mRNA COVID-19 vaccination.
Conclusion	COVID-19 vaccination could induce MEWDS with vision loss.
Conflict of interest	No

Authors 1

Last name	MATSUMIYA
Initials of first name(s)	W
Department	Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine
City	Kobe
Country	Japan

Authors 2

Last name	YASUDA
Initials of first name(s)	E
Department	Department of Ophthalmology, Kakogawa Central City Hospital
City	Kakogawa
Country	Japan

Authors 3

Last name	MAEDA
Initials of first name(s)	Y
Department	Department of Ophthalmology, Kakogawa Central City Hospital
City	Kakogawa
Country	Japan

Authors 4

Last name	KUSUHARA
Initials of first name(s)	S
Department	Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine
City	Kobe
Country	Japan

Authors 5

Last name	NAKAMURA
Initials of first name(s)	M
Department	Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine
City	Kobe
Country	Japan

Authors 6

Last name	HARA
Initials of first name(s)	R
Department	Department of Ophthalmology, Kakogawa Central City Hospital
City	Kakogawa
Country	Japan