| Presentation preference | Oral presentation |
| Title | Paediatric uveitic glaucoma and cataract in the time of biologic therapy |
| Purpose | To investigate rates, timing and visual outcomes of paediatric uveitic glaucoma and cataract in relation to the diagnosis and treatment of the uveitis with steroid sparing / biologic immunosuppression. |
| Methods | Retrospective chart review of all paediatric uveitis patients presenting to the Children’ s Hospital Westmead, Sydney Eye Hospital and Save Sight Institute from 2005- 2020. |
| Results | 111 patients (207 eyes) diagnosed with paediatric uveitis 2005-2020. The majority had bilateral uveitis (n = 89, 80%), 61 patients were female and 48 patients male, the most common aetiological diagnosis was JIA-U (n =65 , 59%), followed by idiopathic uveitis (n = 33, 29.6%) and anatomical diagnosis was 84% anterior uveitis and 16% non-anterior uveitis. Over 50% eyes diagnosed with uveitis developed raised IOP, close to 50% presumed to be steroid induced,
43 eyes (21%) had glaucoma surgery, 35 eyes had glaucoma drainage devices, 15 eyes had trabeculectomy surgery - the majority prior to 2017. Some eyes had two operations.
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| Conclusion | Control of intraocular inflammation is essential. There should be a
rapid taper any systemic steroids, minimise topical steroid therapy to < 3 x per day (as OHT dose dependent), < 3 months duration, commence step ladder systemic more quickly ( IMT - MTX - Biologic)
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| Conflict of interest | No |
Authors 1
| Last name | ZAGORA |
| Initials of first name(s) | SL |
| Department | Ophthalmology, Sydney Eye Hospital, University of Sydney and Westmead Children' Hospital |
| City | Sydney |
| Country | Australia |
Authors 2
| Last name | Karaconji |
| Initials of first name(s) | TK |
| Department | Ophthalmology, Sydney Eye Hospital, University of Sydney and Westmead Children' Hospital |
| City | Sydney |
| Country | Australia |
Authors 3
| Last name | McCluskey |
| Initials of first name(s) | PJ |
| Department | Ophthalmology, Sydney Eye Hospital, University of Sydney |
| City | Sydney |
| Country | Australia |
Authors 4
| Last name | Grigg |
| Initials of first name(s) | J |
| Department | Ophthalmology, Sydney Eye Hospital, University of Sydney and Westmead Children' Hospital |
| City | Sydney |
| Country | Australia |
