| Presentation preference | Oral presentation |
| Title | Consensus Guidelines for Initiating Anti-Tubercular Therapy in Tubercular Choroiditis |
| Accept poster if oral is not possible ? | Yes |
| Purpose | The diagnosis and management of tubercular uveitis poses significant conundrums. Current guidelines and literature are insufficient to guide physicians regarding the administration of anti-tubercular therapy (ATT). An international, expert-led consensus initiative by the Collaborative Ocular Tuberculosis Study (COTS) group developed evidence- and experience-based recommendations for the treatment of tubercular choroiditis. |
| Methods | An international expert steering subcommittee of COTS group identified clinical questions and conducted a systematic review of the published literature on the use of ATT for tubercular choroiditis. Using a smart online questionnaire, 81 global experts generated preliminary consensus statements for initiating ATT in tubercular choroiditis, utilizing Oxford levels of medicine evidence. COTS group members met in November 2018 to refine these consensus statements by a two-step modified Delphi process. |
| Results | 162 clinical scenarios were identified around when to initiate ATT in tubercular serpiginous-like choroiditis, tuberculoma and tubercular focal or multifocal choroiditis. Seventy consensus statements addressed the initiation of ATT and 12 on the use of adjunctive therapies in tubercular choroiditis were developed. |
| Conclusion | Consensus guidelines were developed to guide the initiation of ATT in tubercular choroiditis, based on literature, expert opinion and practical experience, to bridge the gap between clinical need and medical evidence. |
| Conflict of interest | No |
Author 1
| Last name | TESTI |
| Initials of first name(s) | I |
| City | Padova |
| Country | Italy |
Author 2
| Last name | Agrawal |
| Initials of first name(s) | R |
| City | Singapore |
| Country | Singapore |
Author 3
| Last name | Mahajan |
| Initials of first name(s) | S |
| City | Stanford |
| Country | United States |
Author 4
| Last name | Agarwal |
| Initials of first name(s) | A |
| City | Chandigarh |
| Country | India |
Author 5
| Last name | Kempen |
| Initials of first name(s) | JH |
| City | Boston |
| Country | United States |
Author 6
| Last name | Douglas |
| Initials of first name(s) | AJ |
| City | Baltimore |
| Country | United States |
Author 7
| Last name | Smith |
| Initials of first name(s) | JR |
| City | Adelaide |
| Country | Australia |
Author 8
| Last name | Nguyen |
| Initials of first name(s) | QD |
| City | Stanford |
| Country | United States |
Author 9
| Last name | Pavesio |
| Initials of first name(s) | C |
| City | Chandigarh |
| Country | India |
Author 10
| Last name | Gupta |
| Initials of first name(s) | V |
| City | Chandigarh |
| Country | India |
