This abstract is assigned to sessions
| Presentation preference | Poster and Rapid fire |
| Title | Toxoplasmosis in Sydney Australia - a Retrospective cohort |
| Accept poster if oral is not possible ? | Yes |
| Purpose | to determine the seveity and clinical course of ocular toxoplasmosis in a major Australian referral center |
| Methods | Retrospective review of patient files who presented to Sydney Eye Hospital between 2007 and 2017 with clinical features consistent with ocular toxoplasmosis. Visual acuity and relapse rate compared to other studies in ocular toxoplasmosis |
| Results | 48 patients with ocular toxoplasmosis who presented to Sydney Eye Hospital during the period of observation. The median age was 35.5 (IQR 21-50) with 29 (60%) having no previous symptomatic episodes or evidence of chorioretinal scarring. Visual acuity at presentation was 0.51 or 6/19 (SE 0.096) and at follow up 0.31 or 6/9 (SE 0.094). 9 patients experienced a recurrence during the period of observation with time to recurrence 2.2 years (SE 0.45). The relapse rate (1 or more) 0.09/person-year. Location of lesion was predominantly within the vascular arcades (n=44) with macular involvement in 9 patients. Most patients received clindamycin therapy (n=34). |
| Conclusion | Patients with ocular toxoplasmosis had fewer recurrences compared with other published series and had better visual recovery. The majority of patients received clindamycin and oral prednisolone which was well tolerated with pyrimethazine and sulfadiazine reserved for those with macula involving disease. |
| Conflict of interest | No |
Author 1
| Last name | YATES |
| Initials of first name(s) | W |
| Department | Save Sight Institute, The University of Sydney |
| City | Sydney |
| Country | Australia |
Author 2
| Last name | Zagora |
| Initials of first name(s) | S |
| Department | Save Sight Institute, The University of Sydney |
| City | Sydney |
| Country | Australia |
Author 3
| Last name | McCluskey |
| Initials of first name(s) | P |
| Department | Save Sight Institute, The University of Sydney |
| City | Sydney |
| Country | Australia |
Author 4
| Last name | Choong |
| Initials of first name(s) | F |
| Department | Department of Infectious Diseases, Prince of Wales |
| City | Sydney |
| Country | Australia |
Author 5
| Last name | Post |
| Initials of first name(s) | J |
| Department | Department of Infectious Diseases, Prince of Wales |
| City | Sydney |
| Country | Australia |
Author 6
| Last name | Wakefield |
| Initials of first name(s) | D |
| Department | School of Medical Sciences, Sydney Australia |
| City | Sydney |
| Country | Australia |
