Characteristics, Etiologies, and Outcomes of Peripheral Ulcerative Keratitis in a Tertiary referral hospital in Thailand: a 10-year study
Purpose
To evaluate characteristics, etiologies, and outcomes of peripheral ulcerative keratitis (PUK) in Thailand.
Methods
Retrospective study.
Results
Forty-three eyes from 34 patients were enrolled with a mean age of 53.44±15.48 years. PUK affected women more than men (1.6:1) and had unilateral lesions more than bilateral lesions (2.8:1). Redness (56.3%) was the most common presenting symptom followed by pain (43.8%) and irritation (40.6%). Three most common etiologies were mooren’s ulcer (52.9%), rheumatoid arthritis (20.6%), and graves’ disease (8.8%). Corneal thinning was significantly more common in unilaterality (p=0.004) and less common in the lesion at the superior cornea (p=0.031). Perforation was found in 5 eyes (11.6%) and recurrence after treatment was found in 8 eyes (18.6%).
Conclusion
Nearly half of PUK is associated with several systemic causes so careful physical examination and investigation are important. Unilateral lesions could be a potential risk factor in identifying patients at risk of thinning which might prevent further damage to the eye and vision loss.
Conflict of interest
No
Authors 1
Last name
KEOROCHANA
Initials of first name(s)
N
Department
Ophthalmology
City
Bangkok
Country
Thailand
Authors 2
Last name
Kitsirilarp
Initials of first name(s)
W
Department
Ophthalmology
City
Bangkok
Country
Thailand
Authors 3
Last name
Chuephanich
Initials of first name(s)
P
Department
Ophthalmology
City
Bangkok
Country
Thailand
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