Rubella Virus-associated uveitis (RVAU): clinic and complications
Purpose
To describe the clinical findings of patients (PTs) positive for RV in aqueous humor analysis
Methods
Retrospective study including PTs diagnosed with RVAU between May 2018-June 2021. Demographic, ophthalmological variables and the dates of microbiological diagnosis, first and last visit, were collected
Results
Fifteen PTs, 17 eyes were included. Mean age at first visit was 48±13 years, all were Caucasian, 9 males (60%), 53% (9/17) were intermediate uveitis (IU) and the rest iridocyclitis (IC). All of them had: chronic course, diffuse keratic precipitates, diffuse iris atrophy, anterior tyndall ≤ 0.5+ and vitreous ≥ 0.5+ (≥ 1+ in 29.4%: 5 /17). Heterochromia was present in 69.2% (9/13), iris nodules in 59% (10/17), chorioretinal scars in 41% (7/17), and hyphema after diagnostic paracentesis in 35.3% (6/17). After a median follow-up of 7.37 (ICR 9.68) years, 14 eyes (82.3%) maintained the visual acuity (VA) (mean 0.67±0.37) ≥ than baseline (mean 0.5±0.38). The median time interval from first visit to microbiological diagnosis was 7.19 (ICR 9.43) years. All had cataracts, 12/15 (80%) underwent surgery and were, together with persistent vitreous opacities 3/17 (17.6%), the causes of reversible VA reduction, 35.3% (6/17) had ocular hypertension and 11.7% required filtering surgery. Two PTs had been treated with long-term immunosuppressive therapy
Conclusion
In our series, RVAU behaves as a low-grade UI or IC, predominantly unilateral, in middle-aged patients, with iris, vitreous and cataract involvement, manifestations similar Fuchs uveitis syndrome
Conflict of interest
No
Authors 1
Last name
BELMONTE GRAU
Initials of first name(s)
M.
Department
Ophthalmology H.U. de La Princesa
City
Madrid
Country
Spain
Authors 2
Last name
González-Guijarro
Initials of first name(s)
J
Department
Opthalmology H.U. de La Princesa
City
Madrid
Country
Spain
Authors 3
Last name
Escribano López
Initials of first name(s)
P.
Department
Opthalmology H. U. Puerta de Hierro
City
Madrid
Country
Spain
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