This abstract is assigned to sessions
| Presentation preference | Oral presentation |
| Title | Oral Phospholipidic Curcumin in Juvenile Idiopathic Arthritis-Associated Uveitis |
| Accept poster if oral is not possible ? | Yes |
| Purpose | To evaluate the efficacy and the safety of the adjunctive treatment with curcumin-phosphatidylcholine complex in children affected by Juvenile idiopathic arthritis (JIA) -associated uveitis. |
| Methods | In this retrospective, longitudinal study, we treated patients with JIA uveitis and residual low-grade inflammatory activity in the anterior chamber with one tablet of curcumin-phosphatidylcholine complex per day, over a year. Inactivity of uveitis was defined as complete disappearance of flare at the slit-lamp examination and values <10 ph/ms at Laser Flare Meter. |
| Results | A total of 22 out of 27 patients (81%) achieved inactivity at the end of the study. Five patients (19%) remained stable throughout the follow-up. Overall, the treatment was safe and well tolerated. |
| Conclusion | Adjunctive therapy with curcumin in patients affected by JIA-associated uveitis improves mild chronic anterior chamber flare and presents a good safety profile. Anterior chamber inflammation should be minimized to avoid sight-threatening complications. |
| Conflict of interest | No |
Author 1
| Last name | MISEROCCHI |
| Initials of first name(s) | E |
| Department | Department of Ophthalmology, Ospedale San Raffaele Scientific Institute, University Vita-Salute, Mi |
| City | Milan |
| Country | Italy |
Author 2
| Last name | Giuffre |
| Initials of first name(s) | C |
| Department | Department of Ophthalmology, Ospedale San Raffaele Scientific Institute, University Vita-Salute, Mi |
| City | Milan |
| Country | Italy |
Author 3
| Last name | Cicinelli |
| Initials of first name(s) | MV |
| Department | Department of Ophthalmology, Ospedale San Raffaele Scientific Institute, University Vita-Salute, Mi |
| City | Milan |
| Country | Italy |
Author 4
| Last name | Marchese |
| Initials of first name(s) | A |
| Department | Department of Ophthalmology, Ospedale San Raffaele Scientific Institute, University Vita-Salute, Mi |
| City | Milan |
| Country | Italy |
Author 5
| Last name | Modorati |
| Initials of first name(s) | G |
| Department | Department of Ophthalmology, Ospedale San Raffaele Scientific Institute, University Vita-Salute, Mi |
| City | Milan |
| Country | Italy |
Author 6
| Last name | Bandello |
| Initials of first name(s) | F |
| Department | Department of Ophthalmology, Ospedale San Raffaele Scientific Institute, University Vita-Salute, Mi |
| City | Milan |
| Country | Italy |
