This abstract is assigned to sessions
| Presentation preference | Poster and Rapid fire |
| Title | Intravitreal Aflibercept as the Adjuvant Therapy of Presumed Primary Uveal Melanoma - Case report |
| Accept poster if oral is not possible ? | Yes |
| Purpose | To report a case of presumed primary uveal melanoma. |
| Methods | Interventional case report. |
| Results | This is a 74-year-old female who complained of blurred vision in the right eye for 6 months. Her BCVA was 0.1. Fundus autofluorescence showed hypo-autofluorescent appearance and OCT demonstrated subretinal fluid and marked retinal edema. FA showed hypofluorescent in the early phase and heterogeneously hyperfluorescent in the late phase. B-scan showed a dome-shaped lesion with a medium-to-high homogeneous reflectivity and a high height to base ratio. A choroidal tumor was suspected, so she was referred to the oncologist and systemic malignancy had ruled out. MRI showed a T1 moderately high signal and T2 moderately low signal mass lesion. Enhancement with gadolinium contrast was noted. Choroidal melanoma was suspected. Transpupillary thermotherapy and 3 weekly 4mg intravitreal bevacizumab were performed. Only slightly less retinal edema was noted. The subretinal fluid persisted. Confluent transpupillary thermotherapy and 2 weekly intravitreal 4 mg aflibercept were performed. Retinal edema and subretinal fluid subsided markedly. Her vision improved to 0.8. The macula had remained fluid-free for 3 months; however, the mass persisted. |
| Conclusion | Intravitreal aflibercept could be considered as the adjuvant therapy of presumed primary uveal melanoma. More cases and longer follow-up are mandatory. |
| Conflict of interest | No |
Author 1
| Last name | LIN |
| Initials of first name(s) | CJ |
| Department | Department of Ophthalmology, China Medical University Hospital; Department of Optometry, Asia Uni |
| City | Taichung |
| Country | Taiwan |
Author 2
| Last name | Huang |
| Initials of first name(s) | YT |
| City | Taichung |
| Country | Taiwan |
Author 3
| Last name | Hsia |
| Initials of first name(s) | NY |
| City | Taichung |
| Country | Taiwan |
