Nl-Fr

View abstract

This abstract is assigned to session Free Papers : Posters on Display - Series 201-2..
Presentation preference Oral presentation
TitleEffectiveness of Adalimumab in Adult and Paediatric Palestinian Patients with Non-infectious Uveitis
Accept poster if oral is not possible ?Yes
PurposeEvaluating ADA efficacy in Palestinians with non-infectious uveitis.
MethodsWe included 16 patients (31 eyes) who attended clinics at St John Eye Hospital in East Jerusalem between March 2021 and March 2022. There was variability in follow-up times and as such, we aimed to gather data from appointments closest to 6 months post-ADA initiation (range: 5-9 months). Data was collected retrospectively from computer clinic notes. Analysis was done using descriptive statistics, the Wilcoxon Signed-Rank test, and the Chi-Square test.
ResultsOur cohort consisted of both pediatric (n=7) and adult patients (n=9). The mean prednisolone dose at the follow-up visit was 7.3mg, compared to 10.3mg at the start of treatment (p = 0.445). Most patients reduced their doses of concomitant corticosteroid-sparing agents, and 10 subjects stopped them altogether. In addition, good control of intraocular inflammation was noted in over 80% of the cohort (p < 0.001) at the follow-up visit. Three patients (18.8%) experienced a recurrence of the disease and needed to increase their oral prednisolone dose.
ConclusionA majority of patients (80%) responded well to ADA and achieved good disease control.
Conflict of interestNo
1
Last nameERAKAT
Initials of first name(s)s
Departmentophthalmology
Cityjerusalem
CountryIsrael