Pediatric Pars Planitis: Clinical characteristics and the role of RNFL thickness on OCT in disease monitoring
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Yes
Purpose
To study the role of RNFL thickness on OCT in the assessment and monitoring of children with pars planitis.
Methods
Demographic, OCT and Fluorescein Angiography (FA) data were obtained retrospectively between 7/2010 and 12/2023, from Hadassah Hospital medical records.
Results
Included were 29 children (50 eyes) with a mean age at diagnosis of 7.9±2.9 years (69% males, 72.4% bilateral). The most prevalent signs were snowballs (67.4%), iritis (40%) and papillitis (30.4%). Nine eyes (18%) had CME on OCT. Mean LogMAR BCVA was 0.47±0.6, and mean BIO score was 1.7±1.4. Out of 26 eyes with available FA, 20 eyes (80% of 25 eyes with available OD view) and 15 eyes (62.5% of 24 eyes with available view of the macula) had optic disc and macular leakage respectively. Mean RNFL thickness (28 eyes) was 209.6±179 μm. 22 eyes (78.6%) had RNFL thickness ≥130 μm, which was significantly associated with BIO score, iritis, papillitis, immunmodulatory therapy and biologic therapy.
During the follow-up period of 12 months, BCVA improved and BIO score, and RNFL thickness decreased significantly. RNFL thickness was significantly associated with BIO score at 3 months, and with BCVA at 3 and 6 months.
Conclusion
RNFL thickness is increased and is associated with more
severe presentation in pediatric pars planitis. OCT is a non-invasive imaging modality that could serve as a potential imaging biomarker in disease monitoring.
Conflict of interest
No
1
Last name
ABU AL-HALAWA
Initials of first name(s)
D
Department
Ophthalmology
City
Jerusalem
Country
Israel
2
Last name
AMER
Initials of first name(s)
R
Department
Ophthalmology
City
Jerusalem
Country
Israel
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