The Effectiveness of Wide Field OCTA in the Diagnosis and Monitoring of Retinal Vessel and Choroidal Inflammation
Accept poster if oral is not possible ?
Yes
Purpose
To assess the validity of SS-OCTA in diagnosing and monitoring treatment response in patients with retinal vasculitis and/or choroiditis through direct comparison with FA and ICGA.
Methods
Patients with retinal vasculitis and/or choroiditis, for whom wide-field SS-OCTA and FA/ICGA have been performed on the same day at two or more visits, have been identified. The color retinal thickness map was superimposed on a 12X12 mm en-face flow scan of a customized segmentation to demonstrate perivascular retinal thickening in the setting of retinal vasculitis. A montage image was created to allow for analysis of both the macula and near periphery by combining 5 of the modified en-face scans. The montage image was then compared to early and late-phase FA images.
Montage OCTA en-face flow slabs at the level of the choriocapillaris and choroid were also analyzed and compared to findings on early and late phases of ICGA scans in patients with choroiditis.
For all patients, imaging was obtained at ≥2 visits to allow for comparison of imaging modalities at different points in a given patient’s disease course.
Results
19 eyes from 10 patients were analyzed. OCT-A montage images were found to be an effective tool for detecting retinal vasculitis and treatment response, as perivascular thickening correlated well with vascular leaking/staining seen on FA. OCT-A en-face flow scans were found to be an effective tool for monitoring choroiditis, as characteristic flow voids were seen in areas that corresponded with hypofluorescent spots seen on ICGA.
Conclusion
SS-OCTA is a useful imaging tool for diagnosing and monitoring retinal vasculitis and choroiditis in patients with chorioretinal inflammation.
Conflict of interest
No
1
Last name
HARRIGILL
Initials of first name(s)
M
Department
Dean McGee Eye Institute/University of Oklahoma Department of Ophthalmology
City
Oklahoma City
Country
United States
2
Last name
Nguyen
Initials of first name(s)
M
Department
Dean McGee Eye Institute/University of Oklahoma College of Medicine
City
Oklahoma City
Country
United States
3
Last name
Noori
Initials of first name(s)
J
Department
Dean McGee Eye Institute/University of Oklahoma Department of Ophthalmology
City
Oklahoma City
Country
United States
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