An overview of the management of punctate inner choroidopathy (PIC) at University Hospital Southampton
Purpose
To investigate the management and long-term outcome of patients diagnosed with PIC
Methods
We searched for the number of patients who were treated for punctate inner choroidopathy over a 5-year period. We then analysed the patient demographics, visual outcomes and treatment options of these patients.
Results
A total of 17 patients were included in this study. The average age was 45.8 years. There were 15 females and 2 males. The majority had both eyes involved and 4 patients had 1 eye involved. 13 eyes of 21 patients developed secondary CNV, 12 of which received anti-VEGF treatment. Of those who received anti-VEGF injection, 3 had oral Prednisolone initiated on the day when active CNV is seen. Overall, 8 of 21 patients were started on immunosuppressive treatment (IMT), 6 of which also received intravitreal anti-VEGF for secondary CNV. The average number of injections received in patients treated for secondary CNV with anti-VEGF alone (n=5) was 7, anti-VEGF + Prednisolone (n=3) was 9 and anti-VEGF + IMT (n = 8) was 4. Bevacizumab was the most common choice of anti-VEGF. There was no significant difference of the mean visual acuity at presentation (Logmar 0.3, n = 34 eyes) when compared to at last follow-up visit (Logmar 0.4, p = 0.46).
Conclusion
Patients with PIC and secondary CNV who received anti-VEGF followed by IMT required less number of injections when compared to those treated with anti-VEGF injection alone. Combined treatment of long-term IMT with intravitreal injection could be useful in the management of PIC with secondary CNV to reduce the risk of CNV recurrence.
Conflict of interest
No
Authors 1
Last name
KALOGEROPOULOS
Initials of first name(s)
D
Department
Uveitis Service, University of Southampton
City
Southampton
Country
United Kingdom
Authors 2
Last name
RAHMAN
Initials of first name(s)
N
Department
Uveitis Service, University of Southampton
City
Southampton
Country
United Kingdom
Authors 3
Last name
CHATZIRALLIS
Initials of first name(s)
A
Department
Uveitis Service, University of Southampton
City
Southampton
Country
United Kingdom
Authors 4
Last name
HALL
Initials of first name(s)
N
Department
Uveitis Service, University of Southampton
City
Southampton
Country
United Kingdom
Authors 5
Last name
AFSHAR
Initials of first name(s)
F
Department
Uveitis Service, University of Southampton
City
Southampton
Country
United Kingdom
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