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TitleVogt-Koyanagi-Harada disease following a serology-proven Bartonella henselae retinitis: a case report
PurposeTo report a case of Vogt-Koyanagi-Harada (VKH) disease following a serology-confirmed bartonella henselae retinitis
MethodsA single case report
ResultsA 41-year-old female patient presented with a central scotoma in her right eye (RE). Fundoscopic examination showed a focal retinitis with a macular star in the RE. Work-up revealed positive bartonellosis serology. The patient was treated with oral azithromycine and oral steroids during four weeks with subsequent healing of the retinitis lesion. Three months after initial presentation, the patient complained of loss of vision in both eyes. Ophthalmological examination showed a best-corrected visual acuity (BCVA) of 20/200 on both eyes, bilateral granulomatous panuveitis with bilateral multifocal exudative retinal detachment. Results of multimodal imaging were consistent with the diagnosis of acute VKH disease. Given the history of positive bartonellosis serology, the patient was treated with doxycycline (200mg/day) for six weeks in association with intravenous methylprednisolone for 5 days followed by oral steroids and progressive tapering. At three-month follow-up, BCVA improved from 20/200 to 20/20 in both eyes associated with resolution of clinical and structural OCT changes
ConclusionOur case suggests that bartonella henselae infection might be a non-previously reported infectious trigger of VKH disease in genetically predisposed patients. Alternatively, bartonella henselae infection might manifest with panuveitis mimicking VKH disease.
Conflict of interestNo
Authors 1
Last nameKHAIRALLAH
Initials of first name(s)Molk
DepartmentDepartment of Ophthalmology, Tahar Sfar University Hospital
CityMahdia
CountryTunisia
Authors 2
Last nameNABI
Initials of first name(s)Wejd
DepartmentDepartment of Ophthalmology, Fattouma Bourguiba University Hospital
CityMonastir
CountryTunisia
Authors 3
Last nameAMMARI
Initials of first name(s)Wafa
DepartmentDepartement of Ophthalmology, Taher Sfar University Hospital
CityMahdia
CountryTunisia
Authors 4
Last nameBEN SAIDI
Initials of first name(s)Ouss
DepartmentDepartment of Ophthalmology, Fattouma Bourguiba University Hospital
CityMonastir
CountryTunisia
Authors 5
Last nameABROUG
Initials of first name(s)Nesr
DepartmentDepartment of Ophthalmology, Fattouma Bourguiba University Hospital
CityMonastir
CountryTunisia
Authors 6
Last nameKHAIRALLAH
Initials of first name(s)Monc
DepartmentDepartment of Ophthalmology, Fattouma Bourguiba University Hospital
CityMonastir
CountryTunisia