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This abstract is assigned to session Poster Session - On Display Posters nr 200 ... 299
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TitleEpidemiology, Treatment, and Outcome of Juvenile Idiopathic Arthritis-associated Uveitis: a Multi-institutional Study in Taiwan
PurposeTo evaluate the epidemiological characteristics and clinical outcomes of patients with Juvenile Idiopathic Arthritis (JIA)-associated uveitis in Taiwan. The study aims to provide valuable insights to understand the specific pattern of JIA in Taiwan, and improve patient outcomes, and identify potential risk factors associated with poor prognosis
MethodsIn this retrospective, multi-institutional study, we analyzed the medical records of patients diagnosed with JIA-associated uveitis between 2001 and 2019 from the Chang Gung Research database, which covers approximately 10% of total medical service volume in Taiwan. Data on demographics, clinical features, treatment regimens, and follow-up outcomes were collected and analyzed.
ResultsA total of 722 JIA patients and 44 patients (6%) with JIA-associated uveitis were identified in the study period. The mean age at diagnosis for JIA-uveitis was 9.6±4.2 years, a female-to-male ratio of 43%:57%. Anterior uveitis accounted for 88.6%, while panuveitis 9.1% and posterior uveitis 2.3%. 57.9% uveitis patients recurred in 6 months after cessation of the DMARDs. 31.6% of female uveitis patients and 12.0% of male uveitis patients had eye complications. Age less than 6 years showed a more progressive disease course and worse visual prognosis than age more than 6.
ConclusionCompared to other nations, Low prevalence of uveitis in JIA (6.1%), more male than female (6:4), and relative late onset of JIA (9.6 y/o) can be found. Further research on risk stratification and individualized treatment strategies is warranted to improve patient outcomes in this population.
Conflict of interestNo
Authors 1
Last nameHWANG
Initials of first name(s)YS
DepartmentOphthalmology
CityLinkou
CountryTaiwan
Authors 2
Last nameWu
Initials of first name(s)PY
DepartmentOphthalmology
CityLInkou
CountryTaiwan
Authors 3
Last nameKang
Initials of first name(s)EYC
DepartmentOphthalmology
CityLinkou
CountryTaiwan