High resolution imaging of ocular inflammation by flood illumination adaptive optics ophthalmoscopy: a comparison with Multimodal Retinal Imaging
Purpose
To use both methods of imaging SD-OCT and flood illumination adaptive optics ophthalmoscopy (AOO) to study features of retinal vessels during the course of posterior/ intermediate uveitis.
Methods
Venous/ arteries diameters in 13 eyes (12 patients) with posterior uveitis of various causes were quantitatively analyzed by AOO and SD-OCT. Six eyes of 5 of those patients had quantitative data follow-up. AOO measurements were done with AODetect using the en face image and the SD-OCT images with ImageJ using the cross sectional image
Results
The caliber vessels measurements by SD-OCT did not correlate with those obtained by corresponding AOO. SD-OCT was unreliable when measurements of retinal vessels alone because of the ambiguity of the tissues boundaries in edematous retina and lower resolution, however the overall vertical measure including underlying retina was promising.
Conclusion
Both methods are amenable to standardized imaging for the quantitative, for AOO, and semiquantitative, for SD-OCT, for clinical evaluation of uveitis.
Conflict of interest
No
Authors 1
Last name
ERRERA
Initials of first name(s)
MH
Department
UPMC and University of Pittsburgh
City
Pittsburgh
Country
United States
Authors 2
Last name
Kedia
Initials of first name(s)
N
Department
University of Pittsburgh
City
Pittsburgh
Country
United States
Authors 3
Last name
Snyder
Initials of first name(s)
V
Department
University of Pittsburgh
City
Pittsburgh, PA, USA
Country
United States
Authors 4
Last name
Dansingani
Initials of first name(s)
KK
Department
UPMC and University of Pittsburgh
City
Pittsburgh
Country
United States
Authors 5
Last name
Ahmad
Initials of first name(s)
I
Department
University of Pittsburgh
City
Pittsburgh
Country
United States
Authors 6
Last name
Thompson
Initials of first name(s)
A
Department
University of Pittsburgh
City
Pittsburgh
Country
United States
Authors 7
Last name
Satcho
Initials of first name(s)
E
Department
University of Pittsburgh
City
Pittsburgh
Country
United States
Authors 8
Last name
Chhablani
Initials of first name(s)
J
Department
University of Pittsburgh
City
Pittsburgh
Country
United States
Authors 9
Last name
Paques
Initials of first name(s)
M
Department
Sorbonne Universités, UPMC Univ. Paris 06, INSERM, CNRS, Institut de la Vision, Paris, France Centre
City
Paris
Country
France
Authors 10
Last name
Rossi
Initials of first name(s)
E
Department
University of Pittsburgh
City
Pittsburgh
Country
United States
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