Occlusive Retinal Vasculitis in Sydney: 71 eyes of 42 patients.
Accept poster if oral is not possible ?
Yes
Purpose
To review the clinical features, treatment, prognosis, complications and visual outcomes of inflammatory occlusive retinal vasculitis.
Methods
Patients with occlusive retinal vasculitis were identified from a uveitis database. Data was collected from patients’ medical records and scans.
Results
The prevalence of occlusive retinal vasculitis was 2.25%. The median age at presentation was 33 years (range 17-72).
TB-related vasculitis (38.1%) and Behcet disease (31.0%) were the top aetiologies. Initial treatment with high dose oral prednisone was given in 80.9%. The median follow up time was 1.79 years (0-13.6 years). At last follow up, 40.5% were on second line immunosuppression and 28.6% were on a biologic agent. 16 patients were on maintenance oral prednisone at last follow up, with 13 on a dose of = 10mg per day. The median presenting VA was 6/12 (IQR 6/6 to 6/30). The median VA at final follow up was 6/7.5 (IQR 6/6 to 6/18). Complications included: retinal NV in 31.3% of eyes, vitreous haemorrhage in 29.9%, retinal detachment in 4.5% and NV glaucoma in 1.4%. Pan retinal photocoagulation for NV or ischaemia was done in 46.3% of eyes. 9 eyes underwent intra-vitreal Anti-VEGF treatment (13.4%) and 8 eyes underwent vitrectomy to clear vitreous haemorrhage (11.9%).
Conclusion
The most common aetiologies were presumed TB associated vasculitis and Behcet disease, which reflect the ethnic composition of the cohort. Early systemic treatment of active disease with immunosuppression, and anti TB therapy where indicated, as well as local therapy for NV by PRP, intra-vitreal anti-VEGF can help preserve central visual acuity.
Conflict of interest
No
Author 1
Last name
ALI
Initials of first name(s)
NQ
Department
Ophthalmology
City
Sydney
Country
Australia
Author 2
Last name
Zagora
Initials of first name(s)
S
Department
Ophthalmology
City
Sydney
Country
Australia
Author 3
Last name
McCluskey
Initials of first name(s)
P
Department
Ophthalmology
City
Sydney
Country
Australia
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