Effectiveness of Adalimumab in Adult and Paediatric Palestinian Patients with Non-infectious Uveitis
Accept poster if oral is not possible ?
Yes
Purpose
Evaluating ADA efficacy in Palestinians with non-infectious uveitis.
Methods
We included 16 patients (31 eyes) who attended clinics at St John Eye Hospital in East Jerusalem between March 2021 and March 2022. There was variability in follow-up times and as such, we aimed to gather data from appointments closest to 6 months post-ADA initiation (range: 5-9 months). Data was collected retrospectively from computer clinic notes. Analysis was done using descriptive statistics, the Wilcoxon Signed-Rank test, and the Chi-Square test.
Results
Our cohort consisted of both pediatric (n=7) and adult patients (n=9). The mean prednisolone dose at the follow-up visit was 7.3mg, compared to 10.3mg at the start of treatment (p = 0.445). Most patients reduced their doses of concomitant corticosteroid-sparing agents, and 10 subjects stopped them altogether. In addition, good control of intraocular inflammation was noted in over 80% of the cohort (p < 0.001) at the follow-up visit. Three patients (18.8%) experienced a recurrence of the disease and needed to increase their oral prednisolone dose.
Conclusion
A majority of patients (80%) responded well to ADA and achieved good disease control.
Conflict of interest
No
1
Last name
ERAKAT
Initials of first name(s)
s
Department
ophthalmology
City
jerusalem
Country
Israel
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