| Presentation preference | Oral presentation |
| Title | ---PRE-RECORDED --- Pediatric Pars Planitis: Clinical characteristics and the role of RNFL thickness on OCT in disease monitoring |
| Accept poster if oral is not possible ? | Yes |
| Purpose | To study the role of RNFL thickness on OCT in the assessment and monitoring of children with pars planitis. |
| Methods | Demographic, OCT and Fluorescein Angiography (FA) data were obtained retrospectively between 7/2010 and 12/2023, from Hadassah Hospital medical records. |
| Results | Included were 29 children (50 eyes) with a mean age at diagnosis of 7.9±2.9 years (69% males, 72.4% bilateral). The most prevalent signs were snowballs (67.4%), iritis (40%) and papillitis (30.4%). Nine eyes (18%) had CME on OCT. Mean LogMAR BCVA was 0.47±0.6, and mean BIO score was 1.7±1.4. Out of 26 eyes with available FA, 20 eyes (80% of 25 eyes with available OD view) and 15 eyes (62.5% of 24 eyes with available view of the macula) had optic disc and macular leakage respectively. Mean RNFL thickness (28 eyes) was 209.6±179 μm. 22 eyes (78.6%) had RNFL thickness ≥130 μm, which was significantly associated with BIO score, iritis, papillitis, immunmodulatory therapy and biologic therapy.
During the follow-up period of 12 months, BCVA improved and BIO score, and RNFL thickness decreased significantly. RNFL thickness was significantly associated with BIO score at 3 months, and with BCVA at 3 and 6 months. |
| Conclusion | RNFL thickness is increased and is associated with more
severe presentation in pediatric pars planitis. OCT is a non-invasive imaging modality that could serve as a potential imaging biomarker in disease monitoring. |
| Conflict of interest | No |
1
| Last name | ABU AL-HALAWA |
| Initials of first name(s) | D |
| Department | Ophthalmology |
| City | Jerusalem |
| Country | Israel |
2
| Last name | AMER |
| Initials of first name(s) | R |
| Department | Ophthalmology |
| City | Jerusalem |
| Country | Israel |